Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.

Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation.

Intracellular Toll-like receptors (TLRs) expressed by dendritic cells recognize nucleic acids derived from pathogens and play an important role in the immune responses against the influenza virus (IAV), a single-stranded RNA sensed by different receptors including TLR7. However, the importance of TL...

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Bibliographic Details
Main Authors: Sophia Maschalidi, Signe Hässler, Fany Blanc, Fernando E Sepulveda, Mira Tohme, Michel Chignard, Peter van Endert, Mustapha Si-Tahar, Delphyne Descamps, Bénédicte Manoury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002841&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002841&type=printable

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