Antiviral Activity of Zinc Finger Antiviral Protein (ZAP) in Different Virus Families

The CCCH-type zinc finger antiviral protein (ZAP) in humans, specifically isoforms ZAP-L and ZAP-S, is a crucial component of the cell’s intrinsic immune response. ZAP acts as a post-transcriptional RNA restriction factor, exhibiting its activity during infections caused by retroviruses and alphavir...

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Bibliographic Details
Main Authors: Kívia Queiroz de Andrade, Claudio Cesar Cirne-Santos
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/12/12/1461