Unsupervised Flow Cytometry Analysis Allows for an Accurate Identification of Minimal Residual Disease Assessment in Acute Myeloid Leukemia

Unsupervised Flow Cytometry Analysis Allows for an Accurate Identification of Minimal Residual Disease Assessment in Acute Myeloid Leukemia

The assessment of minimal residual disease (MRD) is increasingly considered to monitor response to therapy in hematological malignancies. In acute myeloblastic leukemia (AML), molecular MRD (mMRD) is possible for about half the patients while multiparameter flow cytometry (MFC) is more broadly avail...

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Bibliographic Details
Main Authors: Jean Philippe Vial, Nicolas Lechevalier, Francis Lacombe, Pierre-Yves Dumas, Audrey Bidet, Thibaut Leguay, François Vergez, Arnaud Pigneux, Marie C. Béné
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
acute myeloid leukemia
molecular markers
multiparameter flow cytometry
minimal/measurable residual disease
unsupervised analysis
FlowSOM
Online Access:https://www.mdpi.com/2072-6694/13/4/629

Internet

https://www.mdpi.com/2072-6694/13/4/629

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