Renal subcapsular delivery of PGE2 promotes kidney repair by activating endogenous Sox9+ stem cells

Renal subcapsular delivery of PGE2 promotes kidney repair by activating endogenous Sox9+ stem cells

Summary: Prostaglandin E2 (PGE2) has recently been recognized to play a role in immune regulation and tissue regeneration. However, the short half-life of PGE2 limits its clinical application. Improving the delivery of PGE2 specifically to the target organ with a prolonged release method is highly d...

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Bibliographic Details
Main Authors: Shang Chen, Haoyan Huang, Yue Liu, Chen Wang, Xiaoniao Chen, Yuqiao Chang, Yuhao Li, Zhikun Guo, Zhibo Han, Zhong-Chao Han, Qiang Zhao, Xiang-Mei Chen, Zongjin Li
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Drug delivery system
Pathophysiology
Cell biology
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221012116

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http://www.sciencedirect.com/science/article/pii/S2589004221012116

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