Rapid activation of hematopoietic stem cells

Abstract Adult hematopoietic stem cells (HSCs) in the bone marrow (BM) are quiescent. Following perturbations, such as blood loss or infection, HSCs may undergo activation. Surprisingly, little is known about the earliest stages of HSCs activation. We utilize surface markers of HSCs activation, CD69...

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Bibliographic Details
Main Authors: Roshina Thapa, Erez Elfassy, Leonid Olender, Omri Sharabi, Roi Gazit
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-023-03377-6