PKCμ promotes keratinocyte cell migration through Cx43 phosphorylation-mediated suppression of intercellular communication

Summary: Downregulation of intercellular communication through suppression of gap junctional conductance is necessary during wound healing. Connexin 43 (Cx43), a prominent gap junction protein in skin, is downregulated following wounding to restrict communication between keratinocytes. Previous stud...

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Bibliographic Details
Main Authors: Renju Pun, Ann M. Cavanaugh, Emily Aldrich, Olivia Tran, Justin C. Rudd, Laura A. Hansen, Brian J. North
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224002542