Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.

Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.

TGF-β, a mediator of pulmonary fibrosis, is a genetic modifier of CF respiratory deterioration. The mechanistic relationship between TGF-β signaling and CF lung disease has not been determined.To investigate myofibroblast differentiation in CF lung tissue as a novel pathway by which TGF-β signaling...

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Bibliographic Details
Main Authors: William T Harris, David R Kelly, Yong Zhou, Dezhi Wang, Mark MacEwen, James S Hagood, J P Clancy, Namasivayam Ambalavanan, Eric J Sorscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3741283?pdf=render

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http://europepmc.org/articles/PMC3741283?pdf=render

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