Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.
TGF-β, a mediator of pulmonary fibrosis, is a genetic modifier of CF respiratory deterioration. The mechanistic relationship between TGF-β signaling and CF lung disease has not been determined.To investigate myofibroblast differentiation in CF lung tissue as a novel pathway by which TGF-β signaling...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3741283?pdf=render |