The Influence of Tacrolimus on Cellular Morphology, Cellular Viability, Osteogenic Differentiation, and mRNA Expression within Stem Cell Spheroids

The Influence of Tacrolimus on Cellular Morphology, Cellular Viability, Osteogenic Differentiation, and mRNA Expression within Stem Cell Spheroids

<i>Background and Objectives</i>: Tacrolimus is a macrolide lactone compound derived from the bacterium <i>Streptomyces tsukubensis</i>, widely known as an immunosuppressant. In basic research, the effects of tacrolimus on osteogenic differentiation have been tested using mes...

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Bibliographic Details
Main Authors: Won-Jong Park, Sung-Hoon Han, Hyun-Jin Lee, Ju-Hwan Kim, Hye-Jung Song, Jun-Beom Park
Format: Article
Language:English
Published: MDPI AG 2024-04-01
Series:Medicina
Subjects:
cell survival
cell differentiation
cellular spheroids
osteogenesis
stem cells
tacrolimus
Online Access:https://www.mdpi.com/1648-9144/60/5/702

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https://www.mdpi.com/1648-9144/60/5/702

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