Co-culture of the bone and bone marrow: a novel way to obtain mesenchymal stem cells with enhanced osteogenic ability for fracture healing in SD rats

Co-culture of the bone and bone marrow: a novel way to obtain mesenchymal stem cells with enhanced osteogenic ability for fracture healing in SD rats

Abstract Background Mesenchymal stem cells (MSCs) have great potential for the repair and regeneration of bone fracture, but their optimal origins remain controversial. Methods Bone marrow-MSCs (BM-MSCs) and bone-bone marrow-MSCs (B-BM-MSCs) were isolated from 12 SD rats, and the morphology, MSC-ass...

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Bibliographic Details
Main Authors: Cong Zhu, Mo Sha, Huixiang Jiang, Jianbiao Lin, Weibin Lin, Wenchang Li, Xiaoshan Chen, Guofeng Huang, Zhenqi Ding
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Mesenchymal stem cells
Co-culture
Osteogenic differentiation
Bone fracture
Healing
Online Access:http://link.springer.com/article/10.1186/s13018-019-1346-z

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http://link.springer.com/article/10.1186/s13018-019-1346-z

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