The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11

The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11

Abstract Tripartite motif-containing protein 7 (TRIM7), as an E3 ligase, plays an important regulatory role in various physiological and pathological processes. However, the role of TRIM7 in gastric cancer (GC) is still undefined. Our study detected the expression of TRIM7 in clinical specimens and...

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Bibliographic Details
Main Authors: Qishuai Chen, Tongtong Zhang, Runzhi Zeng, Kunmiao Zhang, Bingjun Li, Zhenguo Zhu, Xiaomin Ma, Yun Zhang, Linchuan Li, Jiankang Zhu, Guangyong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
TRIM7
GC
SLC7A11
Ferroptosis
Ubiquitination
Online Access:https://doi.org/10.1038/s41598-024-56746-3

Internet

https://doi.org/10.1038/s41598-024-56746-3

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