Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives

Synthesis and Anticancer Evaluation of New 1,3,4-Oxadiazole Derivatives

In order to develop novel chemotherapeutic agents with potent anticancer activities, a series of new 2,5-diaryl/heteroaryl-1,3,4-oxadiazoles were designed and synthesized. The structures of the new compounds were established using elemental analyses, IR and NMR spectral data. The compounds were eval...

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Bibliographic Details
Main Authors: Camelia Elena Stecoza, George Mihai Nitulescu, Constantin Draghici, Miron Teodor Caproiu, Octavian Tudorel Olaru, Marinela Bostan, Mirela Mihaila
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
cytotoxic agents
apoptosis induction
HT-29 cells
MDA-MB-231 cells
mechanism prediction
STAT inhibitors
Online Access:https://www.mdpi.com/1424-8247/14/5/438

Internet

https://www.mdpi.com/1424-8247/14/5/438

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