Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model.

Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model.

Borrelia burgdorferi is transmitted into the skin of the host where it encounters and interacts with two dendritic cell (DC) subsets; Langerhans cells (LCs) and dermal DCs (DDCs). These cells recognize pathogens via pattern recognition receptors, mature and migrate out of the skin into draining lymp...

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Bibliographic Details
Main Authors: Lauren M K Mason, Alex Wagemakers, Cornelis van 't Veer, Anneke Oei, Wouter J van der Pot, Kalam Ahmed, Tom van der Poll, Teunis B H Geijtenbeek, Joppe W R Hovius
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5047638?pdf=render

Internet

http://europepmc.org/articles/PMC5047638?pdf=render

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