Possibility of adiponectin use to improve islet transplantation outcomes

Abstract Although islet transplantation (ITx) is a promising therapy for severe diabetes mellitus, further advancements are necessary. Adiponectin, an adipokine that regulates lipid and glucose metabolism, exerts favorable effects on islets, such as reinforcement of the insulin-releasing function. T...

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Bibliographic Details
Main Authors: Naoaki Sakata, Gumpei Yoshimatsu, Kiyoshi Chinen, Ryo Kawakami, Shohta Kodama
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04245-0