The roles of the native cell differentiation program aberrantly recapitulated in Drosophila intestinal tumors

Summary: Many tumors recapitulate the developmental and differentiation program of their tissue of origin, a basis for tumor cell heterogeneity. Although stem-cell-like tumor cells are well studied, the roles of tumor cells undergoing differentiation remain to be elucidated. We employ Drosophila gen...

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Bibliographic Details
Main Authors: Inez Keiko Arlyne Pranoto, Jiae Lee, Young V. Kwon
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723012573