A Molecular Dynamics Simulation Study of the Arg206Cys Variant in DNASE1L3 Enzyme

A Molecular Dynamics Simulation Study of the Arg206Cys Variant in DNASE1L3 Enzyme

Genome-wide association studies (GWAS) have identified that one of the autoimmune disease-associated loci, predisposing for the development of Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis (RA) and Systemic Sclerosis (SSc), is the rs35677470 missense variant of the Deoxyribonuclease I lik...

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Bibliographic Details
Main Authors: Manio Skarlatou, Athena Andreou, Elias Christoforides, Trias Thireou
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biology and Life Sciences Forum
Subjects:
<i>DNASE1L3</i>
molecular dynamics simulations
MD
single nucleotide polymorphism
rs35677470
autoimmune diseases
Online Access:https://www.mdpi.com/2673-9976/20/1/10

Internet

https://www.mdpi.com/2673-9976/20/1/10

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