Identification and development of novel indazole derivatives as potent bacterial peptidoglycan synthesis inhibitors

Identification and development of novel indazole derivatives as potent bacterial peptidoglycan synthesis inhibitors

Background: Tuberculosis is well-known airborne disease caused by Mycobacterium tuberculosis. Available treatment regimen was unsuccessful in eradicating the deaths caused by the disease worldwide. Owing to the drawbacks such as prolonged treatment period, side effects, and drug tolerance, there res...

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Bibliographic Details
Main Authors: Prasanthi Malapati, Vagolu Siva Krishna, Sriram Dharmarajan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:International Journal of Mycobacteriology
Subjects:
Biofilm
cell wall synthesis
indazole
thermal shift assay
tuberculosis
Online Access:http://www.ijmyco.org/article.asp?issn=2212-5531;year=2018;volume=7;issue=1;spage=76;epage=83;aulast=Malapati

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http://www.ijmyco.org/article.asp?issn=2212-5531;year=2018;volume=7;issue=1;spage=76;epage=83;aulast=Malapati

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