Proliferative and Cytokine Responses in CTLA4-Ig-Treated Diabetic NOD Mice Transplanted with Microencapsulated Neonatal Porcine ICCs

Our goal is to develop effective islet xenografts for treating human diabetes. We have studied microencapsulated neonatal porcine islet cell clusters (ICCs) transplanted intraperitoneally in spontaneously diabetic NOD mice, where they function to maintain normoglycemia in the autoimmune host. Nonenc...

Full description

Bibliographic Details
Main Authors: Susan A. Safley, Judith A. Kapp, Collin J. Weber
Format: Article
Language:English
Published: SAGE Publishing 2002-10-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/000000002783985413