The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties

Abstract IL-17A and IL-17F are prominent members of the IL-17 family of cytokines that regulates both innate and adaptive immunity. IL-17A has been implicated in chronic inflammatory and autoimmune diseases, and anti-IL-17A antibodies have shown remarkable clinical efficacy in psoriasis and psoriati...

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Detalles Bibliográficos
Autores principales: Arnaud Goepfert, Sylvie Lehmann, Emmanuelle Wirth, Jean-Michel Rondeau
Formato: Artículo
Lenguaje:English
Publicado: Nature Portfolio 2017-08-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-017-08360-9