Dual-Color Bioluminescence Analysis for Quantitatively Monitoring G-Protein-Coupled Receptor and β-Arrestin Interactions

G protein-coupled receptors (GPCRs) are crucial elements in mammalian signal transduction, and are considered to represent potent drug targets. We have previously developed a GPCR assay system in cultured cells based on complementation of split fragments of click beetle (Pyrearinus termitilluminans)...

Full description

Bibliographic Details
Main Authors: Naomi Misawa, Takeaki Ozawa, A.K.M. Kafi, Mitsuru Hattori
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/4/3/457/