Improved Understanding of the High Shear Wet Granulation Process under the Paradigm of Quality by Design Using <i>Salvia miltiorrhiza</i> Granules

Improved Understanding of the High Shear Wet Granulation Process under the Paradigm of Quality by Design Using <i>Salvia miltiorrhiza</i> Granules

Background: High shear wet granulation (HSWG) is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. However, study of HSWG is complex and challenging due to the relatively poor understanding of HSWG, especially for sticky powder-like herbal extra...

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Bibliographic Details
Main Authors: Yi Zhang, Brian Chi-Yan Cheng, Wenjuan Zhou, Bing Xu, Xiaoyan Gao, Yanjiang Qiao, Gan Luo
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Pharmaceutics
Subjects:
high shear wet granulation
quality by design
<i>salvia miltiorrhiza</i> granules
scale-up
regime map
Online Access:https://www.mdpi.com/1999-4923/11/10/519

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https://www.mdpi.com/1999-4923/11/10/519

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