Impact of viral infections on hematopoiesis: From beneficial to detrimental effects on bone marrow output.

The ability of the bone marrow (BM) to generate the copious amounts of blood cells required on a daily basis depends on a highly orchestrated process of proliferation and differentiation of hematopoietic stem and progenitor cells (HSPCs). This process can be rapidly adapted under stress conditions,...

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Bibliographic Details
Main Authors: Maria Fernanda Pascutti, Martje N. Erkelens, Martijn A. Nolte
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00364/full