Suppressor mutations identify amino acids in PAA-1/PR65 that facilitate regulatory RSA-1/B″ subunit targeting of PP2A to centrosomes in C. elegans

Suppressor mutations identify amino acids in PAA-1/PR65 that facilitate regulatory RSA-1/B″ subunit targeting of PP2A to centrosomes in C. elegans

Summary Protein phosphorylation and dephosphorylation is a key mechanism for the spatial and temporal regulation of many essential developmental processes and is especially prominent during mitosis. The multi-subunit protein phosphatase 2A (PP2A) enzyme plays an important, yet poorly characterized r...

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Bibliographic Details
Main Authors: Karen I. Lange, Jeffrey Heinrichs, Karen Cheung, Martin Srayko
Format: Article
Language:English
Published: The Company of Biologists 2012-11-01
Series:Biology Open
Subjects:
C. elegans
Centrosome
Microtubules
Mitotic spindle assembly
PP2A
Protein phosphatase
Online Access:http://bio.biologists.org/content/2/1/88

Internet

http://bio.biologists.org/content/2/1/88

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