First Trimester Plasma MicroRNA Levels Predict Risk of Developing Gestational Diabetes Mellitus

First Trimester Plasma MicroRNA Levels Predict Risk of Developing Gestational Diabetes Mellitus

AimsOur objective is to identify first-trimester plasmatic miRNAs associated with and predictive of GDM.MethodsWe quantified miRNA using next-generation sequencing in discovery (Gen3G: n = 443/GDM = 56) and replication (3D: n = 139/GDM = 76) cohorts. We have diagnosed GDM using a 75-g oral glucose t...

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Bibliographic Details
Main Authors: Cécilia Légaré, Véronique Desgagné, Kathrine Thibeault, Frédérique White, Andrée-Anne Clément, Cédrik Poirier, Zhong Cheng Luo, Michelle S. Scott, Pierre-Étienne Jacques, Patrice Perron, Renée Guérin, Marie-France Hivert, Luigi Bouchard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
biomarkers
epigenetics
next-generation sequencing
pregnancy
ribo-hormones
risk factors
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.928508/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.928508/full

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