IGF1 receptor-targeted black TiO2 nanoprobes for MRI-guided synergetic photothermal-chemotherapy in drug resistant pancreatic tumor

Abstract Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignant tumors with features of matrix barrier caused poor drug permeability, and susceptibility to drug resistance. Herein, a PDAC and its stromal cell dual-targeted photothermal-chemotherapy strategy is explored to loosen th...

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Bibliographic Details
Main Authors: Kaiwei Xu, Lufei Jin, Liu Xu, Yuchao Zhu, Lu Hong, Chunshu Pan, Yanying Li, Junlie Yao, Ruifen Zou, Weiwei Tang, Jianhua Wang, Aiguo Wu, Wenzhi Ren
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-022-01525-3