Ex vivo infection of murine precision-cut lung tissue slices with Mycobacterium abscessus: a model to study antimycobacterial agents

Ex vivo infection of murine precision-cut lung tissue slices with Mycobacterium abscessus: a model to study antimycobacterial agents

Abstract Background Multidrug-resistant infections due to Mycobacterium abscessus often require complex and prolonged regimens for treatment. Here, we report the evaluation of a new ex vivo antimicrobial susceptibility testing model using organotypic cultures of murine precision-cut lung slices, an...

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Bibliographic Details
Main Authors: Carmen Amelia Molina-Torres, Oscar Noé Flores-Castillo, Irma Edith Carranza-Torres, Nancy Elena Guzmán-Delgado, Ezequiel Viveros-Valdez, Lucio Vera-Cabrera, Jorge Ocampo-Candiani, Julia Verde-Star, Jorge Castro-Garza, Pilar Carranza-Rosales
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Mycobacterium abscessus
Lung tissue slices
Ex vivo infection
Online Access:http://link.springer.com/article/10.1186/s12941-020-00399-3

Internet

http://link.springer.com/article/10.1186/s12941-020-00399-3

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