Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension

Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension

Abstract Background Despite causing increased morbidity and mortality, pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment, due to incomplete understanding of its pathogenesis. Hypertrophy of pulmonary arterial walls and pruning of the micro...

Full description

Bibliographic Details
Main Authors: Khushboo Goel, Nicholas Egersdorf, Amar Gill, Danting Cao, Scott D. Collum, Soma S. Jyothula, Howard J. Huang, Maor Sauler, Patty J. Lee, Susan Majka, Harry Karmouty-Quintana, Irina Petrache
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Emphysema
Endothelial cells
Smoking
Pulmonary vascular remodeling
Group 3 pulmonary hypertension
Online Access:https://doi.org/10.1186/s12931-022-02267-4

Internet

https://doi.org/10.1186/s12931-022-02267-4

Similar Items