Engineering multi-specific antibodies against HIV-1

Engineering multi-specific antibodies against HIV-1

Abstract As increasing numbers of broadly neutralizing monoclonal antibodies (mAbs) against HIV-1 enter clinical trials, it is becoming evident that combinations of mAbs are necessary to block infection by the diverse array of globally circulating HIV-1 strains and to limit the emergence of resistan...

Full description

Bibliographic Details
Main Authors: Neal N. Padte, Jian Yu, Yaoxing Huang, David D. Ho
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Retrovirology
Subjects:
HIV-1
Bispecific antibody
Trispecific antibody
Multi-specific antibody
Neutralizing antibody
Passive immunization
Online Access:http://link.springer.com/article/10.1186/s12977-018-0439-9

Internet

http://link.springer.com/article/10.1186/s12977-018-0439-9

Similar Items