In Vitro and In Vivo Effects of Conventional and Chitosan Nanoparticle-Encapsulated Miltefosine Drug for Treatment of Cutaneous Leishmaniasis

In Vitro and In Vivo Effects of Conventional and Chitosan Nanoparticle-Encapsulated Miltefosine Drug for Treatment of Cutaneous Leishmaniasis

This study aimed to formulate polymer-based chitosan nanoparticles as a drug (miltefosine) delivery system for treating leishmaniasis. Miltefosine-loaded chitosan nanoparticles (MLCNPs) have been synthesized and then characterized by the use of UV-visible spectroscopy, scanning electron microscopy (...

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Bibliographic Details
Main Authors: Rahat Ullah Khan, Momin Khan, Qudrat Ullah, Muhammad Zahoor Khan, Aamir Sohail, Rehmat Islam, Hazrat Bilal, Shakeeb Ullah, Aamir Iqbal
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Medical Sciences Forum
Subjects:
cutaneous leishmaniasis
nanotherapy
animal model
MTT assay
hemolysis assay
Online Access:https://www.mdpi.com/2673-9992/21/1/19

Internet

https://www.mdpi.com/2673-9992/21/1/19

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