IgG Placental Transfer in Healthy and Pathological Pregnancies

Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that provides protection to the infant while his/her humoral response is inefficient. IgG is the only antibody class that significantly crosses the human placenta. This crossing is mediated by FcRn expressed on sync...

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Bibliographic Details
Main Authors: Patricia Palmeira, Camila Quinello, Ana Lúcia Silveira-Lessa, Cláudia Augusta Zago, Magda Carneiro-Sampaio
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/985646