Stimulation of the immune system by a tumor antigen-bearing adenovirus-inspired VLP allows control of melanoma growth

Stimulation of the immune system by a tumor antigen-bearing adenovirus-inspired VLP allows control of melanoma growth

Virus-like particles (VLPs) are versatile protein-based platforms that can be used as a vaccine platform mainly in infectiology. In the present work, we compared a previously designed, non-infectious, adenovirus-inspired 60-mer dodecahedric VLP to display short epitopes or a large tumor model antige...

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Bibliographic Details
Main Authors: Solène Besson, Emilie Boucher, David Laurin, Olivier Manches, Caroline Aspord, Dalil Hannani, Pascal Fender
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
virus-like-particles
antigen display
cancer vaccine
immuno-oncology
melanoma
tumor associated antigens
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050122001760

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http://www.sciencedirect.com/science/article/pii/S2329050122001760

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