Glycine administration attenuates progression of dystrophic pathology in prednisolone-treated dystrophin/utrophin null mice
Abstract Duchenne muscular dystrophy (DMD) is an X-linked genetic disease characterized by progressive muscle wasting and weakness and premature death. Glucocorticoids (e.g. prednisolone) remain the only drugs with a favorable impact on DMD patients, but not without side effects. We have demonstrate...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2019-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-019-49140-x |