MiRNA-190a-5p promotes primordial follicle hyperactivation by targeting PHLPP1 in premature ovarian failure

MiRNA-190a-5p promotes primordial follicle hyperactivation by targeting PHLPP1 in premature ovarian failure

We previously screened 6 differentially expressed miRNAs in ovarian tissues of 4-vinylcyclohexene diepoxide (VCD)-treated premature ovarian failure (POF) model in SD rats, including miRNA-190a-5p, miRNA-98-5p, miRNA-29a-3p, miRNA-144-5p, miRNA-27b-3p, miRNA-151-5p. In this study, to investigate the...

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Bibliographic Details
Main Authors: Yuchi Zhang, Dongwei Han, Xiaoyan Yu, Xinyu Shao, Chuju Zong, Manyu Zhang, Junzhi Wang, Jingwen Liang, Pengling Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
premature ovarian failure (POF)
4-vinylcyclohexene diepoxide (VCD)
miRNA-190a-5p
PHLPP1
AKT
LHR
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1034832/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1034832/full

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