Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Abstract Treatment failure in joint infections is associated with fibrinous, antibiotic-resistant, floating and tissue-associated Staphylococcus aureus aggregates formed in synovial fluid (SynF). We explore whether antibiotic activity could be increased against Staphylococcus aureus aggregates using...

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Bibliographic Details
Main Authors: Neil Zhao, Dylan Curry, Rachel E. Evans, Selin Isguven, Theresa Freeman, John R. Eisenbrey, Flemming Forsberg, Jessica M. Gilbertie, Sophie Boorman, Rachel Hilliard, Sana S. Dastgheyb, Priscilla Machado, Maria Stanczak, Marc Harwood, Antonia F. Chen, Javad Parvizi, Irving M. Shapiro, Noreen J. Hickok, Thomas P. Schaer
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04752-y

Internet

https://doi.org/10.1038/s42003-023-04752-y

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