Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

Nifuroxazide suppresses PD-L1 expression and enhances the efficacy of radiotherapy in hepatocellular carcinoma

Radiation therapy is a primary treatment for hepatocellular carcinoma (HCC), but its effectiveness can be diminished by various factors. The over-expression of PD-L1 has been identified as a critical reason for radiotherapy resistance. Previous studies have demonstrated that nifuroxazide exerts anti...

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Bibliographic Details
Main Authors: Tiesuo Zhao, Pengkun Wei, Congli Zhang, Shijie Zhou, Lirui Liang, Shuoshuo Guo, Zhinan Yin, Sichang Cheng, Zerui Gan, Yuanling Xia, Yongxi Zhang, Sheng Guo, Jiateng Zhong, Zishan Yang, Fei Tu, Qianqing Wang, Jin Bai, Feng Ren, Zhiwei Feng, Huijie Jia
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-03-01
Series:eLife
Subjects:
hepatocellular carcinoma
PD-L1
radiotherapy
cancer immunotherapy
Online Access:https://elifesciences.org/articles/90911

Internet

https://elifesciences.org/articles/90911

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