Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Abstract T helper (Th) cells provide immunity to pathogens but also contribute to detrimental immune responses during allergy and autoimmunity. Th2 cells mediate asthmatic airway inflammation and Th1 cells are involved in the pathogenesis of multiple sclerosis. T cell activation involves complex tra...

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Bibliographic Details
Main Authors: Anna Krone, Yan Fu, Simon Schreiber, Johanna Kotrba, Loisa Borde, Aileen Nötzold, Christoph Thurm, Jonas Negele, Tobias Franz, Sabine Stegemann-Koniszewski, Jens Schreiber, Christoph Garbers, Aniruddh Shukla, Robert Geffers, Burkhart Schraven, Dirk Reinhold, Anne Dudeck, Annegret Reinhold, Andreas J. Müller, Sascha Kahlfuss
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-04827-6

Internet

https://doi.org/10.1038/s41598-022-04827-6

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