Ovarian cancer-associated immune exhaustion involves SPP1+ T cell and NKT cell, symbolizing more malignant progression

Ovarian cancer-associated immune exhaustion involves SPP1+ T cell and NKT cell, symbolizing more malignant progression

BackgroundOvarian cancer (OC) is highly heterogeneous and has a poor prognosis. A better understanding of OC biology could provide more effective therapeutic paradigms for different OC subtypes.MethodsTo reveal the heterogeneity of T cell-associated subclusters in OC, we performed an in-depth analys...

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Bibliographic Details
Main Authors: Kunyu Wang, Hongyi Hou, Yanan Zhang, Miao Ao, Haixia Luo, Bin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Endocrinology
Subjects:
ovarian cancer
SPP1+ T cell
T cell exhaustion
single cell RNA sequencing
immune environment
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1168245/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1168245/full

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