Adipocyte-specific deletion of PIP5K1c reduces diet-induced obesity and insulin resistance by increasing energy expenditure

Adipocyte-specific deletion of PIP5K1c reduces diet-induced obesity and insulin resistance by increasing energy expenditure

Abstract Background Phosphatidylinositol 4-phosphate 5-kinase type I c (PIP5K1c) catalyses the synthesis of phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) by phosphorylating phosphatidylinositol 4 phosphate, which plays multiple roles in regulating focal adhesion formation, invasion, and...

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Bibliographic Details
Main Authors: Guan Huang, Cuishan Yang, Sheng Guo, Miaoling Huang, Liping Deng, Ying Huang, Puxin Chen, Feng Chen, Xiaohong Huang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Lipids in Health and Disease
Subjects:
Obesity
PIP5K1c
Adipose tissue
Energy expenditure
Adipogenesis
Online Access:https://doi.org/10.1186/s12944-021-01616-4

Internet

https://doi.org/10.1186/s12944-021-01616-4

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