Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor.

Insertion of the voltage-sensitive domain into circularly permuted red fluorescent protein as a design for genetically encoded voltage sensor.

Visualization of electrical activity in living cells represents an important challenge in context of basic neurophysiological studies. Here we report a new voltage sensitive fluorescent indicator which response could be detected by fluorescence monitoring in a single red channel. To the best of our...

Full description

Bibliographic Details
Main Authors: Liubov A Kost, Evgeny S Nikitin, Violetta O Ivanova, Uhna Sung, Ekaterina V Putintseva, Dmitry M Chudakov, Pavel M Balaban, Konstantin A Lukyanov, Alexey M Bogdanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184225&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184225&type=printable

Similar Items