PEG-mediated transduction of rAAV as a platform for spatially confined and efficient gene delivery
Abstract Background Recombinant adeno-associated viruses (rAAV) are commonly used vectors for gene delivery in both basic neuroscience and clinical applications due to their nonpathogenic, minimally immunogenic, and sustained expression properties. However, several challenges remain for the wide-sca...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2022-12-01
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Series: | Biomaterials Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40824-022-00322-1 |