PEG-mediated transduction of rAAV as a platform for spatially confined and efficient gene delivery

Abstract Background Recombinant adeno-associated viruses (rAAV) are commonly used vectors for gene delivery in both basic neuroscience and clinical applications due to their nonpathogenic, minimally immunogenic, and sustained expression properties. However, several challenges remain for the wide-sca...

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Bibliographic Details
Main Authors: Liang Zou, Jinfen Wang, Ying Fang, Huihui Tian
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-12-01
Series:Biomaterials Research
Subjects:
Online Access:https://doi.org/10.1186/s40824-022-00322-1