Human alveolar hydrogels promote morphological and transcriptional differentiation in iPSC-derived alveolar type 2 epithelial cells

Human alveolar hydrogels promote morphological and transcriptional differentiation in iPSC-derived alveolar type 2 epithelial cells

Abstract Alveolar type 2 epithelial cells (AT2s) derived from human induced pluripotent stem cells (iAT2s) have rapidly contributed to our understanding of AT2 function and disease. However, while iAT2s are primarily cultured in three-dimensional (3D) Matrigel, a matrix derived from cancerous mouse...

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Bibliographic Details
Main Authors: Evan T. Hoffman, Juan J. Uriarte, Franziska E. Uhl, Korin Eckstrom, Alicia E. Tanneberger, Chloe Becker, Chloe Moulin, Loredana Asarian, Laertis Ikonomou, Darrell N. Kotton, Daniel J. Weiss
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37685-x

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https://doi.org/10.1038/s41598-023-37685-x

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