GNS561 Exhibits Potent Antiviral Activity against SARS-CoV-2 through Autophagy Inhibition

GNS561 Exhibits Potent Antiviral Activity against SARS-CoV-2 through Autophagy Inhibition

Since December 2019, SARS-CoV-2 has spread quickly worldwide, leading to more than 280 million confirmed cases, including over 5,000,000 deaths. Interestingly, coronaviruses were found to subvert and hijack autophagic process to allow their viral replication. Autophagy-modulating compounds thus rapi...

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Bibliographic Details
Main Authors: Eloïne Bestion, Keivan Zandi, Sandrine Belouzard, Julien Andreani, Hubert Lepidi, Marie Novello, Clara Rouquairol, Jean-Pierre Baudoin, Madani Rachid, Bernard La Scola, Jean-Louis Mege, Jean Dubuisson, Raymond F. Schinazi, Soraya Mezouar, Philippe Halfon
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Viruses
Subjects:
GNS561/Ezurpimtrostat
SARS-CoV-2
COVID-19
autophagy
LC3
Online Access:https://www.mdpi.com/1999-4915/14/1/132

Internet

https://www.mdpi.com/1999-4915/14/1/132

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