Cisplatin-induced ototoxicity: From signaling network to therapeutic targets

Cisplatin-induced ototoxicity: From signaling network to therapeutic targets

Administration of cisplatin, a common chemotherapeutic drug, has an inevitable side effect of sensorineural hearing loss. The main etiologies are stria vascularis injury, spiral ganglion degeneration, and hair cell death. Over several decades, the research scope of cisplatin-induced ototoxicity has...

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Bibliographic Details
Main Authors: Xilu Wang, Yingying Zhou, Dali Wang, Yi Wang, Zhaoyu Zhou, Xiulan Ma, Xiaofang Liu, Yaodong Dong
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cisplatin-induced ototoxicity
Inflammation
Oxidative stress
Programmed cell death
Therapeutic targets
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222014342

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http://www.sciencedirect.com/science/article/pii/S0753332222014342

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