Ectopic expression of HIV-1 Tat modifies gene expression in cultured B cells: implications for the development of B-cell lymphomas in HIV-1-infected patients

Ectopic expression of HIV-1 Tat modifies gene expression in cultured B cells: implications for the development of B-cell lymphomas in HIV-1-infected patients

An increased frequency of B-cell lymphomas is observed in human immunodeficiency virus-1 (HIV-1)-infected patients, although HIV-1 does not infect B cells. Development of B-cell lymphomas may be potentially due to the action of the HIV-1 Tat protein, which is actively released from HIV-1-infected ce...

Full description

Bibliographic Details
Main Authors: Anna A. Valyaeva, Maria A. Tikhomirova, Daria M. Potashnikova, Alexandra N. Bogomazova, Galina P. Snigiryova, Aleksey A. Penin, Maria D. Logacheva, Eugene A. Arifulin, Anna A. Shmakova, Diego Germini, Anastasia I. Kachalova, Aleena A. Saidova, Anastasia A. Zharikova, Yana R. Musinova, Andrey A. Mironov, Yegor S. Vassetzky, Eugene V. Sheval
Format: Article
Language:English
Published: PeerJ Inc. 2022-10-01
Series:PeerJ
Subjects:
HIV-1 Tat
B cells
Virus-cell interactions
Gene expression
RNA-seq
Online Access:https://peerj.com/articles/13986.pdf

Internet

https://peerj.com/articles/13986.pdf

Similar Items