Inhibition of 15‐hydroxyprostaglandin dehydrogenase protects neurons from ferroptosis in ischemic stroke

Inhibition of 15‐hydroxyprostaglandin dehydrogenase protects neurons from ferroptosis in ischemic stroke

Abstract Ischemic stroke is an acute serious cerebrovascular disease with high mortality and disability. Ferroptosis is an important regulated cell death (RCD) in ischemic stroke. 15‐Hydroxyprostaglandin dehydrogenase (15‐PGDH), a degrading enzyme of prostaglandin E2 (PGE2), is shown to regulate RCD...

Полное описание

Библиографические подробности
Главные авторы: Yunfei Xu, Kexin Li, Yao Zhao, Lin Zhou, Nina He, Haoduo Qiao, Qing Xu, Huali Zhang, Ying Liu, Jie Zhao
Формат: Статья
Язык:English
Опубликовано: Wiley 2024-01-01
Серии:MedComm
Предметы:
15‐PGDH
ferroptosis
GPX4
ischemic stroke
PGE2
Online-ссылка:https://doi.org/10.1002/mco2.452

Internet

https://doi.org/10.1002/mco2.452

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