Dynamic and redundant regulation of LRRK2 and LRRK1 expression

<p>Abstract</p> <p>Background</p> <p>Mutations within the <it>leucine-rich repeat kinase 2 </it>(<it>LRRK2</it>) gene account for a significant proportion of autosomal-dominant and some late-onset sporadic Parkinson's disease. Elucidation of...

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Bibliographic Details
Main Authors: Dawson Ted M, Dawson Valina L, Coombes Candice E, Lorenz-Deperieux Bettina, Rea Alexis, Moore Darren J, Biskup Saskia, West Andrew B
Format: Article
Language:English
Published: BMC 2007-11-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/102