Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Optimal pharmacotherapy pathway in adults with diabetic peripheral neuropathic pain: the OPTION-DM RCT

Background: The mainstay of treatment for diabetic peripheral neuropathic pain is pharmacotherapy, but the current National Institute for Health and Care Excellence guideline is not based on robust evidence, as the treatments and their combinations have not been directly compared. Objectives: To det...

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Bibliographic Details
Main Authors: Solomon Tesfaye, Gordon Sloan, Jennifer Petrie, David White, Mike Bradburn, Tracey Young, Satyan Rajbhandari, Sanjeev Sharma, Gerry Rayman, Ravikanth Gouni, Uazman Alam, Steven A Julious, Cindy Cooper, Amanda Loban, Katie Sutherland, Rachel Glover, Simon Waterhouse, Emily Turton, Michelle Horspool, Rajiv Gandhi, Deirdre Maguire, Edward Jude, Syed Haris Ahmed, Prashanth Vas, Christian Hariman, Claire McDougall, Marion Devers, Vasileios Tsatlidis, Martin Johnson, Didier Bouhassira, David L Bennett, Dinesh Selvarajah
Format: Article
Language:English
Published: NIHR Journals Library 2022-10-01
Series:Health Technology Assessment
Subjects:
diabetes
painful diabetic neuropathy
pregabalin
duloxetine
amitriptyline
crossover trial
combination treatment
Online Access:https://doi.org/10.3310/RXUO6757

Internet

https://doi.org/10.3310/RXUO6757

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