Morphometric Analysis of Rat Prostate Development: Roles of MEK/ERK and Rho Signaling Pathways in Prostatic Morphogenesis

Morphometric Analysis of Rat Prostate Development: Roles of MEK/ERK and Rho Signaling Pathways in Prostatic Morphogenesis

The molecular mechanisms underlying prostate development can provide clues for prostate cancer research. It has been demonstrated that MEK/ERK signaling downstream of androgen-targeted FGF10 signaling directly induces prostatic branching during development, while Rho/Rho-kinase can regulate prostate...

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Bibliographic Details
Main Authors: Wen-Yang Hu, Parivash Afradiasbagharani, Ranli Lu, Lifeng Liu, Lynn A. Birch, Gail S. Prins
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
prostate
branching morphogenesis
FGF10
ERK1/2
Rho kinase
myosin light chain kinase
Online Access:https://www.mdpi.com/2218-273X/11/12/1829

Internet

https://www.mdpi.com/2218-273X/11/12/1829

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