In Vivo Induction of Myeloid Suppressor Cells and CD4Foxp3 T Regulatory Cells Prolongs Skin Allograft Survival in Mice
Natural CD4 + Foxp3 + T regulatory (Treg) cells can promote transplantation acceptance across major histocompatibility complex (MHC) barriers, while myeloid-derived suppressor cells (MDSCs) inhibit effector T-cell responses in tumor-bearing mice. One outstanding issue is whether combining the potent...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2011-07-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368910X540621 |