Early‐like differentiation status of systemic PD‐1+CD8+ T cells predicts PD‐1 blockade outcome in non‐small cell lung cancer

Early‐like differentiation status of systemic PD‐1+CD8+ T cells predicts PD‐1 blockade outcome in non‐small cell lung cancer

Abstract Objectives Despite remarkable advances in the treatment of non‐small cell lung cancer (NSCLC) with anti‐programmed death (PD)‐1 therapy; only a fraction of patients derives durable clinical benefit. In this study, we investigated whether the differentiation status of systemic CD8+ T cells p...

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Bibliographic Details
Main Authors: Asma Khanniche, Yi Yang, Jie Zhang, Shiqing Liu, Liliang Xia, Huangqi Duan, Yaxian Yao, Bingrong Zhao, Guo‐Ping Zhao, Chengping Hu, Ying Wang, Shun Lu
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Clinical & Translational Immunology
Subjects:
biomarkers
early‐like differentiation
non‐small‐cell lung cancer
PD‐1 blockade
T cells
Online Access:https://doi.org/10.1002/cti2.1406

Internet

https://doi.org/10.1002/cti2.1406

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